Scott Fritz, DVM, ABVT
ToxicologistBeef Cattle Institute
Kansas State University 
Scottfritz@vet.k-state.edu 

Sources 

Alfalfa is the most common source of phytoestrogen exposure in the US.  Other clover species can contribute to the total exposure. 

Mechanism 

Phytoestrogens bind to estrogen receptors in the animal leading to multiple effects. 

Signs 

The most economically important clinical sign associated with phytoestrogens is infertility.  This is especially true in pre-pubescent animals that are exposed and can lead to life-long infertility by disrupting the estrogen-influenced maturation process.  Prolapses have also been associated with feeding high levels of phytoestrogens.  Phytoestrogens do not cause abortion. 

Treatment 

Remove the suspect source. 

Diagnosis 

Phytoestrogen evaluation of suspect feed source.  Clinical improvement following removal. 

Links