This episode of After the Abstract reviews a 2025 study on managing Johne’s disease in beef cattle using different testing and culling strategies in a modeled 300-cow herd. The results showed that testing cows every six months reduced disease prevalence the most, but was the least profitable strategy, even compared with doing nothing. Testing every 24 months provided the best economic balance, lowering prevalence moderately while maintaining the highest net return. The discussion also emphasizes that the prevalence of Johne’s disease in purchased replacement cattle and strong biosecurity practices may influence herd outcomes more than frequent testing.

Article Discused: https://pubmed.ncbi.nlm.nih.gov/41472190/